ARCELL Study Discussion Outline Research question: Existing evidence: Missing evidence layer: Available specimens and time points: Controls and matched pairs: Assay to discuss (Arc-well / wellDR-seq / integrative analysis / other): Pilot purpose (feasibility / evolutionary relationship / mechanistic clues): Proposed scope (distinguish specimens and pairs): Deliverables to agree (QC, CNA, subclones, paired analysis, interpretation): Follow-up validation: Sample, ethics, data and intellectual-property matters: Pilot examples: discuss 3–5 FFPE specimens for feasibility, 3–5 matched pairs for an evolutionary question, or 2–3 suitable fresh specimens for wellDR-seq. These are examples, not definitive study designs or powered sample sizes. No guarantee of a specific publication, grant or positive finding. Timing and fees require agreement. Research use only; not individual clinical care. Contact: research@arcell.bio